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    • TDP-43 loss of function drives aberrant splicing in Parkinson's disease
    • Broad brain biodistribution conferred by an AAV to restore TDP-43 function mitigates Frontotemporal Dementia-like deficits
    • Depletion of TDP-43 exacerbates tauopathy-dependent brain atrophy by sensitizing vulnerable neurons to caspase 3-mediated endoproteolysis of tau in a mouse model of Multiple Etiology Dementia
    • Validation of TDP-43 Splicing Repression as a Therapeutic Strategy for ALS and FTD
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    • Thoughts on Digital Inheritance of Experiences of Famous and Veteran Physicians of Traditional Chinese Medicine
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    • The Correlation Between Olfactory Test and Hippocampal Volume in Alzheimer's Disease and Mild Cognitive Impairment Patients: A Meta-Analysis
    • 柴胡类方对比选择性五羟色胺再摄取抑制剂治疗肿瘤相关抑郁Meta分析
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    • Evaluation of the efficacy and safety of the use of acupuncture for the adjuvant treatment of patients with post-stroke cognitive impairment: protocol for a randomized controlled trial
    • 基于数据挖掘的针刺治疗血管性认知损害选穴组方规律研究
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TDP-43 loss of function drives aberrant splicing in Parkinson's disease

9月 4, 2025·
James W. Brenton
,
Josefine Follett
,
Reta Nirujogi
,
Clara E. Toomey
,
Paula Lopez-Garcia
,
James R. Evans
,
et al.
· 0 分钟阅读时长
bioRxiv
类型
预印本
出版物
bioRxiv
publications
最近更新于 9月 4, 2025
TDP-43 Parkinson's Disease RNA Splicing
Broad brain biodistribution conferred by an AAV to restore TDP-43 function mitigates Frontotemporal Dementia-like deficits 1月 1, 2025 →
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